National Cancer Research Month 2023

National Cancer Research Month 2023

May is National Cancer Research Month. It was first started by the American Association of Cancer Research to shine a light on the importance of cancer research and how it helps millions of people around the world. Every year, many people are affected by cancer and many people benefit from cutting edge cancer research. Many people still die due to cancer so more research needs to be done to save and improve the lives of people with cancer. One particularly hard cancer to treat is mesothelioma. Mesothelioma is a cancer of the lining of certain organs including the lungs, abdomen, heart, and testicles. It is mainly caused by asbestos exposure. When people inhale microscopic asbestos fibers, the fibers become lodged in human tissue. Over time, the fibers cause mesothelioma and other cancers.

One study that is new and interesting is trying to find ways to prevent mesothelioma in people who are exposed to asbestos. Currently, there is no way to stop mesothelioma in people exposed to asbestos. The study is looking at the use of anti-inflammatories and antioxidants to reduce inflammation caused by asbestos fibers. The research depends on the idea that mesothelioma is caused by chronic inflammation caused by asbestos fibers lodged in human tissue. If researchers are correct, the research they are doing could save countless lives.

Another set of researchers is looking to treat mesothelioma by blocking YAP (yes-associated protein) and TEAD (transcriptional enhancer activator domain) within the HIPPO signaling pathway. The HIPPO pathway is crucial for normal cell growth and controlling the immune response. A majority of the time, YAP is over expressed when people have cancer, so cancer growth is intensified. The research looks to block TEAD, which then helps block YAP. The researchers are specifically looking at NF2 mutant cancers because they are dependent on YAP to grow. Research is currently being done to find the best dosage and to find if the treatment is safe and tolerable by patients. More research will be done to determine the effectiveness of the treatment on mesothelioma.

Finally, a study looking at a unique form of radiotherapy was published earlier this year. The radiotherapy in question is accelerated hypofractionated radiotherapy. It is radiotherapy given in a shorter time frame than other radiation treatments. It also consists of higher doses of radiation per session. The study looked at 20 people with pleural mesothelioma treated with this therapy. The researchers wanted to determine if the treatment shrank tumors and was tolerable by patients. The treatment consisted of chemotherapy and accelerated hypofractionated radiotherapy. They were able to find that the median survival rate for patients was 85 percent. The median three-year survival rate was 50 percent. Like other studies, more research needs to be completed to determine safety and effectiveness of the treatment for pleural mesothelioma.

Cancer research is a crucial part of the cancer treatment process. This is especially true for mesothelioma, which is a cancer that is very hard to treat and has no cure. Without past research, people with mesothelioma would not be living as long or have as high of a quality of life as they do now.

Were you exposed to asbestos and later diagnosed with mesothelioma? Contact us today to see if you could be entitled to compensation. Call 412-471-3980 or fill out our contact form and a member of our team will get back to you as soon as possible.

Sources:
“Accelerated Hypofractionated Radiotherapy for Mesothelioma” Mesothelioma Center (March 10, 2023). [Link]
May is National Cancer Research Month” American Association for Cancer Research [Link]
“Researchers are Trying to Find Ways to Prevent Mesothelioma in Asbestos Exposed Individuals” Mesothelioma Center (May 12, 2023). [Link]
“YAP/TEAD Inhibitor is Showing Promising Results for Mesothelioma and NF2-Mutant Cancers” Mesothelioma Center (April 21, 2023). [Link]
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